17 And the dragon was wroth with the woman, and went to make war with the remnant of her seed, which keep the commandments of God, and have the testimony of Jesus Christ.
English Standard Version
17 Then the dragon became furious with the woman and went off to make war on the rest of her offspring, on those who keep the commandments of God and hold to the testimony of Jesus. And he stoodSome manuscripts And I stood, connecting the sentence with 13:1 on the sand of the sea.
17 Helpless with rage, the Dragon raged at the Woman, then went off to make war with the rest of her children, the children who keep God's commands and hold firm to the witness of Jesus.
New King James Version
17 And the dragon was enraged with the woman, and he went to make war with the rest of her offspring, who keep the commandments of God and have the testimony of Jesus Christ.
New Living Translation
17 And the dragon was angry at the woman and declared war against the rest of her children-all who keep God's commandments and maintain their testimony for Jesus.
The church and all her friends might well be called to praise God for deliverance from pagan persecution, though other troubles awaited her. The wilderness is a desolate place, and full of serpents and scorpions, uncomfortable and destitute of provisions; yet a place of safety, as well as where one might be alone. But being thus retired could not protect the woman. The flood of water is explained by many to mean the invasions of barbarians, by which the western empire was overwhelmed; for the heathen encouraged their attacks, in the hope of destroying Christianity. But ungodly men, for their worldly interests, protected the church amidst these tumults, and the overthrow of the empire did not help the cause of idolatry. Or, this may be meant of a flood of error, by which the church of God was in danger of being overwhelmed and carried away. The devil, defeated in his designs upon the church, turns his rage against persons and places. Being faithful to God and Christ, in doctrine, worship, and practice, exposes to the rage of Satan; and will do so till the last enemy shall be destroyed.