21 And the eye cannot say unto the hand, I have no need of thee: nor again the head to the feet, I have no need of you. 22 Nay, much more those members of the body, which seem to be more feeble, are necessary:
English Standard Version
21 The eye cannot say to the hand, "I have no need of you," nor again the head to the feet, "I have no need of you." 22 On the contrary, the parts of the body that seem to be weaker are indispensable,
21 Can you imagine Eye telling Hand, "Get lost; I don't need you"? Or, Head telling Foot, "You're fired; your job has been phased out"? 22 As a matter of fact, in practice it works the other way - the "lower" the part, the more basic, and therefore necessary. You can live without an eye, for instance, but not without a stomach.
New King James Version
21 And the eye cannot say to the hand, "I have no need of you"; nor again the head to the feet, "I have no need of you." 22 No, much rather, those members of the body which seem to be weaker are necessary.
New Living Translation
21 The eye can never say to the hand, "I don't need you." The head can't say to the feet, "I don't need you." 22 In fact, some parts of the body that seem weakest and least important are actually the most necessary.
Matthew Henry's Commentary on 1 Corinthians 12:21-22
Christ and his church form one body, as Head and members. Christians become members of this body by baptism. The outward rite is of Divine institution; it is a sign of the new birth, and is called therefore the washing of regeneration, Titus 3:5. But it is by the Spirit, only by the renewing of the Holy Ghost, that we are made members of Christ's body. And by communion with Christ at the Lord's supper, we are strengthened, not by drinking the wine, but by drinking into one Spirit. Each member has its form, place, and use. The meanest makes a part of the body. There must be a distinction of members in the body. So Christ's members have different powers and different places. We should do the duties of our own place, and not murmur, or quarrel with others. All the members of the body are useful and necessary to each other. Nor is there a member of the body of Christ, but may and ought to be useful to fellow-members. As in the natural body of man, the members should be closely united by the strongest bonds of love; the good of the whole should be the object of all. All Christians are dependent one upon another; each is to expect and receive help from the rest. Let us then have more of the spirit of union in our religion.