21 The Lord will plague you with diseases until he has destroyed you from the land you are entering to possess.
21 The Lord shall make the pestilence cleave unto thee, until he have consumed thee from off the land, whither thou goest to possess it.
21 The Lord will make the pestilence stick to you until he has consumed you off the land that you are entering to take possession of it.
21 God will infect you with The Disease, wiping you right off the land that you're going in to possess.
21 The Lord will make the plague cling to you until He has consumed you from the land which you are going to possess.
21 The Lord will afflict you with diseases until none of you are left in the land you are about to enter and occupy.
Matthew Henry's Commentary on Deuteronomy 28:21
Commentary on Deuteronomy 28:15-44
(Read Deuteronomy 28:15-44)
If we do not keep God's commandments, we not only come short of the blessing promised, but we lay ourselves under the curse, which includes all misery, as the blessing all happiness. Observe the justice of this curse. It is not a curse causeless, or for some light cause. The extent and power of this curse. Wherever the sinner goes, the curse of God follows; wherever he is, it rests upon him. Whatever he has is under a curse. All his enjoyments are made bitter; he cannot take any true comfort in them, for the wrath of God mixes itself with them. Many judgments are here stated, which would be the fruits of the curse, and with which God would punish the people of the Jews, for their apostacy and disobedience. We may observe the fulfilling of these threatenings in their present state. To complete their misery, it is threatened that by these troubles they should be bereaved of all comfort and hope, and left to utter despair. Those who walk by sight, and not by faith, are in danger of losing reason itself, when every thing about them looks frightful.