22 The Lord will strike you with consumption, with fever, with inflammation, with severe burning fever, with the sword, with scorching, and with mildew; they shall pursue you until you perish. 23 And your heavens which are over your head shall be bronze, and the earth which is under you shall be iron. 24 The Lord will change the rain of your land to powder and dust; from the heaven it shall come down on you until you are destroyed. 25 The Lord will cause you to be defeated before your enemies; you shall go out one way against them and flee seven ways before them; and you shall become troublesome to all the kingdoms of the earth. 26 Your carcasses shall be food for all the birds of the air and the beasts of the earth, and no one shall frighten them away. 27 The Lord will strike you with the boils of Egypt, with tumors, with the scab, and with the itch, from which you cannot be healed. 28 The Lord will strike you with madness and blindness and confusion of heart. 29 And you shall grope at noonday, as a blind man gropes in darkness; you shall not prosper in your ways; you shall be only oppressed and plundered continually, and no one shall save you. 30 You shall betroth a wife, but another man shall lie with her; you shall build a house, but you shall not dwell in it; you shall plant a vineyard, but shall not gather its grapes. 31 Your ox shall be slaughtered before your eyes, but you shall not eat of it; your donkey shall be violently taken away from before you, and shall not be restored to you; your sheep shall be given to your enemies, and you shall have no one to rescue them. 32 Your sons and your daughters shall be given to another people, and your eyes shall look and fail with longing for them all day long; and there shall be no strength in your hand. 33 A nation whom you have not known shall eat the fruit of your land and the produce of your labor, and you shall be only oppressed and crushed continually. 34 So you shall be driven mad because of the sight which your eyes see. 35 The Lord will strike you in the knees and on the legs with severe boils which cannot be healed, and from the sole of your foot to the top of your head. 36 The Lord will bring you and the king whom you set over you to a nation which neither you nor your fathers have known, and there you shall serve other gods--wood and stone. 37 And you shall become an astonishment, a proverb, and a byword among all nations where the Lord will drive you. 38 You shall carry much seed out to the field but gather little in, for the locust shall consume it. 39 You shall plant vineyards and tend them, but you shall neither drink of the wine nor gather the grapes; for the worms shall eat them. 40 You shall have olive trees throughout all your territory, but you shall not anoint yourself with the oil; for your olives shall drop off. 41 You shall beget sons and daughters, but they shall not be yours; for they shall go into captivity. 42 Locusts shall consume all your trees and the produce of your land.

Matthew Henry's Commentary on Deuteronomy 28:22-42

Commentary on Deuteronomy 28:15-44

(Read Deuteronomy 28:15-44)

If we do not keep God's commandments, we not only come short of the blessing promised, but we lay ourselves under the curse, which includes all misery, as the blessing all happiness. Observe the justice of this curse. It is not a curse causeless, or for some light cause. The extent and power of this curse. Wherever the sinner goes, the curse of God follows; wherever he is, it rests upon him. Whatever he has is under a curse. All his enjoyments are made bitter; he cannot take any true comfort in them, for the wrath of God mixes itself with them. Many judgments are here stated, which would be the fruits of the curse, and with which God would punish the people of the Jews, for their apostacy and disobedience. We may observe the fulfilling of these threatenings in their present state. To complete their misery, it is threatened that by these troubles they should be bereaved of all comfort and hope, and left to utter despair. Those who walk by sight, and not by faith, are in danger of losing reason itself, when every thing about them looks frightful.