22 The Lord will afflict you with consumption, fever, inflammation, with fiery heat and drought, and with blight and mildew; they shall pursue you until you perish. 23 The sky over your head shall be bronze, and the earth under you iron. 24 The Lord will change the rain of your land into powder, and only dust shall come down upon you from the sky until you are destroyed. 25 The Lord will cause you to be defeated before your enemies; you shall go out against them one way and flee before them seven ways. You shall become an object of horror to all the kingdoms of the earth. 26 Your corpses shall be food for every bird of the air and animal of the earth, and there shall be no one to frighten them away. 27 The Lord will afflict you with the boils of Egypt, with ulcers, scurvy, and itch, of which you cannot be healed. 28 The Lord will afflict you with madness, blindness, and confusion of mind; 29 you shall grope about at noon as blind people grope in darkness, but you shall be unable to find your way; and you shall be continually abused and robbed, without anyone to help. 30 You shall become engaged to a woman, but another man shall lie with her. You shall build a house, but not live in it. You shall plant a vineyard, but not enjoy its fruit. 31 Your ox shall be butchered before your eyes, but you shall not eat of it. Your donkey shall be stolen in front of you, and shall not be restored to you. Your sheep shall be given to your enemies, without anyone to help you. 32 Your sons and daughters shall be given to another people, while you look on; you will strain your eyes looking for them all day but be powerless to do anything. 33 A people whom you do not know shall eat up the fruit of your ground and of all your labors; you shall be continually abused and crushed, 34 and driven mad by the sight that your eyes shall see. 35 The Lord will strike you on the knees and on the legs with grievous boils of which you cannot be healed, from the sole of your foot to the crown of your head. 36 The Lord will bring you, and the king whom you set over you, to a nation that neither you nor your ancestors have known, where you shall serve other gods, of wood and stone. 37 You shall become an object of horror, a proverb, and a byword among all the peoples where the Lord will lead you. 38 You shall carry much seed into the field but shall gather little in, for the locust shall consume it. 39 You shall plant vineyards and dress them, but you shall neither drink the wine nor gather the grapes, for the worm shall eat them. 40 You shall have olive trees throughout all your territory, but you shall not anoint yourself with the oil, for your olives shall drop off. 41 You shall have sons and daughters, but they shall not remain yours, for they shall go into captivity. 42 All your trees and the fruit of your ground the cicada shall take over.

Matthew Henry's Commentary on Deuteronomy 28:22-42

Commentary on Deuteronomy 28:15-44

(Read Deuteronomy 28:15-44)

If we do not keep God's commandments, we not only come short of the blessing promised, but we lay ourselves under the curse, which includes all misery, as the blessing all happiness. Observe the justice of this curse. It is not a curse causeless, or for some light cause. The extent and power of this curse. Wherever the sinner goes, the curse of God follows; wherever he is, it rests upon him. Whatever he has is under a curse. All his enjoyments are made bitter; he cannot take any true comfort in them, for the wrath of God mixes itself with them. Many judgments are here stated, which would be the fruits of the curse, and with which God would punish the people of the Jews, for their apostacy and disobedience. We may observe the fulfilling of these threatenings in their present state. To complete their misery, it is threatened that by these troubles they should be bereaved of all comfort and hope, and left to utter despair. Those who walk by sight, and not by faith, are in danger of losing reason itself, when every thing about them looks frightful.