4 This is the case of the manslayer, that shall flee there and live: whoever kills his neighbor unawares, and didn’t hate him in time past; 5 as when a man goes into the forest with his neighbor to chop wood, and his hand fetches a stroke with the axe to cut down the tree, and the head slips from the handle, and lights on his neighbor, so that he dies; he shall flee to one of these cities and live: 6 lest the avenger of blood pursue the manslayer, while his heart is hot, and overtake him, because the way is long, and strike him mortally; whereas he was not worthy of death, inasmuch as he didn’t hate him in time past. 7 Therefore I command you, saying, You shall set apart three cities for yourselves. 8 If Yahweh your God enlarges your border, as he has sworn to your fathers, and gives you all the land which he promised to give to your fathers; 9 if you keep all this commandment to do it, which I command you this day, to love Yahweh your God, and to walk ever in his ways; then you shall add three cities more for yourselves, besides these three: 10 that innocent blood not be shed in the midst of your land, which Yahweh your God gives you for an inheritance, and so blood be on you.

Matthew Henry's Commentary on Deuteronomy 19:4-10

Commentary on Deuteronomy 19:1-13

(Read Deuteronomy 19:1-13)

Here is the law settled between the blood of the murdered, and the blood of the murderer; provision is made, that the cities of refuge should be a protection, so that a man should not die for that as a crime, which was not his willing act. In Christ, the Lord our Righteousness, refuge is provided for those who by faith flee unto him. But there is no refuge in Jesus Christ for presumptuous sinners, who go on still in their trespasses. Those who flee to Christ from their sins, shall be safe in him, but not those who expect to be sheltered by him in their sins.