4 "This is the provision for the manslayer, who by fleeing there may save his life. If any one kills his neighbor unintentionally without having been at enmity with him in time past-- 5 as when a man goes into the forest with his neighbor to cut wood, and his hand swings the axe to cut down a tree, and the head slips from the handle and strikes his neighbor so that he dies--he may flee to one of these cities and save his life; 6 lest the avenger of blood in hot anger pursue the manslayer and overtake him, because the way is long, and wound him mortally, though the man did not deserve to die, since he was not at enmity with his neighbor in time past. 7 Therefore I command you, You shall set apart three cities. 8 And if the Lord your God enlarges your border, as he has sworn to your fathers, and gives you all the land which he promised to give to your fathers-- 9 provided you are careful to keep all this commandment, which I command you this day, by loving the Lord your God and by walking ever in his ways--then you shall add three other cities to these three, 10 lest innocent blood be shed in your land which the Lord your God gives you for an inheritance, and so the guilt of bloodshed be upon you.

Matthew Henry's Commentary on Deuteronomy 19:4-10

Commentary on Deuteronomy 19:1-13

(Read Deuteronomy 19:1-13)

Here is the law settled between the blood of the murdered, and the blood of the murderer; provision is made, that the cities of refuge should be a protection, so that a man should not die for that as a crime, which was not his willing act. In Christ, the Lord our Righteousness, refuge is provided for those who by faith flee unto him. But there is no refuge in Jesus Christ for presumptuous sinners, who go on still in their trespasses. Those who flee to Christ from their sins, shall be safe in him, but not those who expect to be sheltered by him in their sins.