45 All these curses shall come upon you, pursuing and overtaking you until you are destroyed, because you did not obey the Lord your God, by observing the commandments and the decrees that he commanded you. 46 They shall be among you and your descendants as a sign and a portent forever. 47 Because you did not serve the Lord your God joyfully and with gladness of heart for the abundance of everything, 48 therefore you shall serve your enemies whom the Lord will send against you, in hunger and thirst, in nakedness and lack of everything. He will put an iron yoke on your neck until he has destroyed you. 49 The Lord will bring a nation from far away, from the end of the earth, to swoop down on you like an eagle, a nation whose language you do not understand, 50 a grim-faced nation showing no respect to the old or favor to the young. 51 It shall consume the fruit of your livestock and the fruit of your ground until you are destroyed, leaving you neither grain, wine, and oil, nor the increase of your cattle and the issue of your flock, until it has made you perish. 52 It shall besiege you in all your towns until your high and fortified walls, in which you trusted, come down throughout your land; it shall besiege you in all your towns throughout the land that the Lord your God has given you. 53 In the desperate straits to which the enemy siege reduces you, you will eat the fruit of your womb, the flesh of your own sons and daughters whom the Lord your God has given you. 54 Even the most refined and gentle of men among you will begrudge food to his own brother, to the wife whom he embraces, and to the last of his remaining children, 55 giving to none of them any of the flesh of his children whom he is eating, because nothing else remains to him, in the desperate straits to which the enemy siege will reduce you in all your towns. 56 She who is the most refined and gentle among you, so gentle and refined that she does not venture to set the sole of her foot on the ground, will begrudge food to the husband whom she embraces, to her own son, and to her own daughter, 57 begrudging even the afterbirth that comes out from between her thighs, and the children that she bears, because she is eating them in secret for lack of anything else, in the desperate straits to which the enemy siege will reduce you in your towns. 58 If you do not diligently observe all the words of this law that are written in this book, fearing this glorious and awesome name, the Lord your God, 59 then the Lord will overwhelm both you and your offspring with severe and lasting afflictions and grievous and lasting maladies. 60 He will bring back upon you all the diseases of Egypt, of which you were in dread, and they shall cling to you. 61 Every other malady and affliction, even though not recorded in the book of this law, the Lord will inflict on you until you are destroyed. 62 Although once you were as numerous as the stars in heaven, you shall be left few in number, because you did not obey the Lord your God. 63 And just as the Lord took delight in making you prosperous and numerous, so the Lord will take delight in bringing you to ruin and destruction; you shall be plucked off the land that you are entering to possess. 64 The Lord will scatter you among all peoples, from one end of the earth to the other; and there you shall serve other gods, of wood and stone, which neither you nor your ancestors have known. 65 Among those nations you shall find no ease, no resting place for the sole of your foot. There the Lord will give you a trembling heart, failing eyes, and a languishing spirit. 66 Your life shall hang in doubt before you; night and day you shall be in dread, with no assurance of your life. 67 In the morning you shall say, "If only it were evening!" and at evening you shall say, "If only it were morning!"-because of the dread that your heart shall feel and the sights that your eyes shall see. 68 The Lord will bring you back in ships to Egypt, by a route that I promised you would never see again; and there you shall offer yourselves for sale to your enemies as male and female slaves, but there will be no buyer.

Matthew Henry's Commentary on Deuteronomy 28:45-68

Commentary on Deuteronomy 28:45-68

(Read Deuteronomy 28:45-68)

If God inflicts vengeance, what miseries his curse can bring upon mankind, even in this present world! Yet these are but the beginning of sorrows to those under the curse of God. What then will be the misery of that world where their worm dieth not, and their fire is not quenched! Observe what is here said of the wrath of God, which should come and remain upon the Israelites for their sins. It is amazing to think that a people so long the favourites of Heaven, should be so cast off; and yet that a people so scattered in all nations should be kept distinct, and not mixed with others. If they would not serve God with cheerfulness, they should be compelled to serve their enemies. We may justly expect from God, that if we do not fear his fearful name, we shall feel his fearful plagues; for one way or other God will be feared. The destruction threatened is described. They have, indeed, been plucked from off the land, verse 63. Not only by the Babylonish captivity, and when Jerusalem was destroyed by the Romans; but afterwards, when they were forbidden to set foot in Jerusalem. They should have no rest; no rest of body, ver. 65, but be continually on the remove, either in hope of gain, or fear of persecution. No rest of the mind, which is much worse. They have been banished from city to city, from country to country; recalled, and banished again. These events, compared with the favour shown to Israel in ancient times, and with the prophecies about them, should not only excite astonishment, but turn unto us for a testimony, assuring us of the truth of Scripture. And when the other prophecies of their conversion to Christ shall come to pass, the whole will be a sign and a wonder to all the nations of the earth, and the forerunner of a general spread of true christianity. The fulfilling of these prophecies upon the Jewish nation, delivered more than three thousand years ago, shows that Moses spake by the Spirit of God; who not only foresees the ruin of sinners, but warns of it, that they may prevent it by a true and timely repentance, or else be left without excuse. And let us be thankful that Christ hath redeemed us from the curse of the law, by being made a curse for us, and bearing in his own person all that punishment which our sins merit, and which we must otherwise have endured for ever. To this Refuge and salvation let sinners flee; therein let believers rejoice, and serve their reconciled God with gladness of heart, for the abundance of his spiritual blessings.