45 All these curses are going to come on you. They're going to hunt you down and get you until there's nothing left of you because you didn't obediently listen to the Voice of God, your God, and diligently keep his commandments and guidelines that I commanded you. 46 The curses will serve as signposts, warnings to your children ever after. 47 Because you didn't serve God, your God, out of the joy and goodness of your heart in the great abundance, 48 you'll have to serve your enemies whom God will send against you. Life will be famine and drought, rags and wretchedness; then he'll put an iron yoke on your neck until he's destroyed you. 49 Yes, God will raise up a faraway nation against you, swooping down on you like an eagle, a nation whose language you can't understand, 50 a mean-faced people, cruel to grandmothers and babies alike. 51 They'll ravage the young of your animals and the crops from your fields until you're destroyed. They'll leave nothing behind: no grain, no wine, no oil, no calves, no lambs - and finally, no you. 52 They'll lay siege to you while you're huddled behind your town gates. They'll knock those high, proud walls flat, those walls behind which you felt so safe. They'll lay siege to your fortified cities all over the country, this country that God, your God, has given you. 53 And you'll end up cannibalizing your own sons and daughters that God, your God, has given you. When the suffering from the siege gets extreme, you're going to eat your own babies. 54 The most gentle and caring man among you will turn hard, his eye evil, against his own brother, his cherished wife, and even the rest of his children who are still alive, 55 refusing to share with them a scrap of meat from the cannibal child-stew he is eating. He's lost everything, even his humanity, in the suffering of the siege that your enemy mounts against your fortified towns. 56 And the most gentle and caring woman among you, a woman who wouldn't step on a wildflower, will turn hard, her eye evil, against her cherished husband, against her son, against her daughter, 57 against even the afterbirth of her newborn infants; she plans to eat them in secret - she does eat them! - because she has lost everything, even her humanity, in the suffering of the siege that your enemy mounts against your fortified towns. 58 If you don't diligently keep all the words of this Revelation written in this book, living in holy awe before This Name glorious and terrible, God, your God, 59 then God will pound you with catastrophes, you and your children, huge interminable catastrophes, hideous interminable illnesses. 60 He'll bring back and stick you with every old Egyptian malady that once terrorized you. 61 And yes, every disease and catastrophe imaginable - things not even written in the Book of this Revelation - God will bring on you until you're destroyed. 62 Because you didn't listen obediently to the Voice of God, your God, you'll be left with a few pitiful stragglers in place of the dazzling stars-in-the-heavens multitude you had become. 63 And this is how things will end up: Just as God once enjoyed you, took pleasure in making life good for you, giving you many children, so God will enjoy getting rid of you, clearing you off the Earth. He'll weed you out of the very soil that you are entering in to possess. 64 He'll scatter you to the four winds, from one end of the Earth to the other. You'll worship all kinds of other gods, gods neither you nor your parents ever heard of, wood and stone no-gods. 65 But you won't find a home there, you'll not be able to settle down. God will give you a restless heart, longing eyes, a homesick soul. 66 You will live in constant jeopardy, terrified of every shadow, never knowing what you'll meet around the next corner. 67 In the morning you'll say, "I wish it were evening." In the evening you'll say, "I wish it were morning." Afraid, terrorized at what's coming next, afraid of the unknown, because of the sights you've witnessed. 68 God will ship you back to Egypt by a road I promised you'd never see again. There you'll offer yourselves for sale, both men and women, as slaves to your enemies. And not a buyer to be found.

Matthew Henry's Commentary on Deuteronomy 28:45-68

Commentary on Deuteronomy 28:45-68

(Read Deuteronomy 28:45-68)

If God inflicts vengeance, what miseries his curse can bring upon mankind, even in this present world! Yet these are but the beginning of sorrows to those under the curse of God. What then will be the misery of that world where their worm dieth not, and their fire is not quenched! Observe what is here said of the wrath of God, which should come and remain upon the Israelites for their sins. It is amazing to think that a people so long the favourites of Heaven, should be so cast off; and yet that a people so scattered in all nations should be kept distinct, and not mixed with others. If they would not serve God with cheerfulness, they should be compelled to serve their enemies. We may justly expect from God, that if we do not fear his fearful name, we shall feel his fearful plagues; for one way or other God will be feared. The destruction threatened is described. They have, indeed, been plucked from off the land, verse 63. Not only by the Babylonish captivity, and when Jerusalem was destroyed by the Romans; but afterwards, when they were forbidden to set foot in Jerusalem. They should have no rest; no rest of body, ver. 65, but be continually on the remove, either in hope of gain, or fear of persecution. No rest of the mind, which is much worse. They have been banished from city to city, from country to country; recalled, and banished again. These events, compared with the favour shown to Israel in ancient times, and with the prophecies about them, should not only excite astonishment, but turn unto us for a testimony, assuring us of the truth of Scripture. And when the other prophecies of their conversion to Christ shall come to pass, the whole will be a sign and a wonder to all the nations of the earth, and the forerunner of a general spread of true christianity. The fulfilling of these prophecies upon the Jewish nation, delivered more than three thousand years ago, shows that Moses spake by the Spirit of God; who not only foresees the ruin of sinners, but warns of it, that they may prevent it by a true and timely repentance, or else be left without excuse. And let us be thankful that Christ hath redeemed us from the curse of the law, by being made a curse for us, and bearing in his own person all that punishment which our sins merit, and which we must otherwise have endured for ever. To this Refuge and salvation let sinners flee; therein let believers rejoice, and serve their reconciled God with gladness of heart, for the abundance of his spiritual blessings.