17 Cain knew his wife, and she conceived and bore Enoch; and he built a city, and called the name of the city after the name of his son, Enoch. 18 To Enoch was born Irad; and Irad was the father of Me-hu'ja-el, and Me-hu'ja-el the father of Me-thu'sha-el, and Me-thu'sha-el the father of Lamech.

19 And Lamech took two wives; the name of the one was Adah, and the name of the other Zillah. 20 Adah bore Jabal; he was the father of those who dwell in tents and have cattle.

Matthew Henry's Commentary on Genesis 4:17-20

Commentary on Genesis 4:16-18

(Read Genesis 4:16-18)

Cain cast off all fear of God, and attended no more on God's ordinances. Hypocritical professors, who dissemble and trifle with God, are justly left to themselves to do something grossly scandalous. So they throw off that form of godliness to which they have been a reproach, and of which they deny the power. Cain went out from the presence of the Lord, and we never find that he came into it again, to his comfort. The land Cain dwelt in was called the land of Nod, which means, 'shaking,' or 'trembling,' and so shows the restlessness and uneasiness of his own spirit, or 'the land of a vagabond:' they that depart from God cannot find rest any where else. Those on earth who looked for the heavenly city, chose to dwell in tabernacles or tents; but Cain, as not minding that city, built one on earth. Thus all who are cursed of God seek their settlement and satisfaction here below.

Commentary on Genesis 4:19-24

(Read Genesis 4:19-24)

One of Cain's wicked race is the first recorded, as having broken the law of marriage. Hitherto, one man had but one wife at a time; but Lamech took two. Wordly things, are the only things that carnal, wicked people set their hearts upon, and are most clever and industrious about. So it was with this race of Cain. Here was a father of shepherds, and a father of musicians, but not a father of the faithful. Here is one to teach about brass and iron, but none to teach the good knowledge of the Lord: here are devices how to be rich, and how to be mighty, and how to be merry; but nothing of God, of his fear and service. Present things fill the heads of most. Lamech had enemies, whom he had provoked. He draws a comparison betwixt himself and his ancestor Cain; and flatters himself that he is much less criminal. He seems to abuse the patience of God in sparing Cain, into an encouragement to expect that he may sin unpunished.