16 And Manasseh shed very much innocent blood, till he had filled Jerusalem [with it] from one end to another; beside his sin with which he made Judah to sin, in doing evil in the sight of Jehovah.

Matthew Henry's Commentary on 2 Kings 21:16

Commentary on 2 Kings 21:10-18

(Read 2 Kings 21:10-18)

Here is the doom of Judah and Jerusalem. The words used represent the city emptied and utterly desolate, yet not destroyed thereby, but cleansed, and to be kept for the future dwelling of the Jews: forsaken, yet not finally, and only as to outward privileges, for individual believers were preserved in that visitation. The Lord will cast off any professing people who dishonour him by their crimes, but never will desert his cause on earth. In the book of Chronicles we read of Manasseh's repentance, and acceptance with God; thus we may learn not to despair of the recovery of the greatest sinners. But let none dare to persist in sin, presuming that they may repent and reform when they please. There are a few instances of the conversion of notorious sinners, that none may despair; and but few, that none may presume.